ADIZEP (Tirzepatide)

Innovator’s Specs

 ADIZEP Solution for Injection 5mg/0.5mL

Each 0.5 mL Pen contains:

Tirzepatide…5mg

(Pre-filled syringe with disposable autoinjector)

Innovator’s Specs

 ADIZEP Solution for Injection 7.5mg/0.5mL

Each 0.5 mL Pen contains:

Tirzepatide…7.5mg

(Pre-filled syringe with disposable autoinjector)

Innovator’s Specs

 ADIZEP Solution for Injection 10mg/0.5mL

Each 0.5 mL Pen contains:

Tirzepatide…10mg

(Pre-filled syringe with disposable autoinjector)

Innovator’s Specs

 ADIZEP Solution for Injection 12.5mg/0.5mL

Each 0.5 mL Pen contains:

Tirzepatide…12.5mg

(Pre-filled syringe with disposable autoinjector)

Innovator’s Specs

 ADIZEP Solution for Injection 15mg/0.5mL

Each 0.5 mL Pen contains:

Tirzepatide…15mg

(Pre-filled syringe with disposable autoinjector)

Mechanism of Action

Tirzepatide is a GIP receptor and GLP-1 receptor agonist. It is an amino-acid sequence including a C20 fatty diacid that enables albumin binding and prolongs the half-life. Tirzepatide selectively binds to and activates both the GIP and GLP-1 receptors, the targets for native GIP and GLP-1. Tirzepatide enhances first and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. In addition, both GIP and GLP-1 receptors are expressed in the areas of the brain important to appetite regulation.